International Psychogeriatrics
Volume 15, Supplement 1 - 2003
Small Vessel Disease: Neuropathology DAVID G. MUNOZ
ABSTRACT. Diseases of small cerebral blood vessels are heterogeneous in etiology and
manifestations. Lipohyalinosis, venous collagenosis, amyloid angiopathy, and CADASIL affect
different populations of blood vessels. Large and small hemorrhages, lacunae, cortical
microinfarcts, and leukoaraiosis are the most important consequences of the small vessel
angiopathies. Altered permeability as well as ischemia may be involved in the pathogenesis of
the latter.
