International Psychogeriatrics
Volume 15, Supplement 1 - 2003
Assessment of Executive Function in Clinical Trials RAIJA YLIKOSKI AND TUOMO HÄNNINEN
ABSTRACT. Cerebrovascular disease and stroke are related to high risk of cognitive impairment.
One of the main neuropsychological features in vascular cognitive impairment and vascular
dementia is executive dysfunction. Definition of the essential subcomponents and concepts of
executive function is important before determining the methodology in clinical trials. The
scientific research and new methods on this topic are rapidly growing. We present some most
commonly used neuropsychological tests and discuss the methodological aspects in light of
clinical trials.